LOUISVILLE, Ky. -- Lamar Jackson lost the ball, No. 11 Louisville lost the game to rival Kentucky and it remains to be seen how it all will impact the Heisman Trophy race that once belonged to the Cardinals quarterback just a few weeks ago.The Louisville sophomore had a record-setting day on Saturday, even striking a spontaneous Heisman pose following a game-tying touchdown midway through the fourth quarter before all that jubilation turned to disappointment after a 41-38 loss. Jackson didnt want to talk about the Heisman after the game, instead focusing on his team was trying to digest another mistake-filled loss.This loss is gonna be hard, Jackson said. Its our rival. Our seniors didnt go out right.Kentuckys seniors are going out on a high note.Austin MacGinnis 47-yard field goal with 12 seconds remaining gave the Wildcats the upset, an unexpected turnaround after Jackson was driving the Cardinals toward a go-ahead score late in the game. Jacksons fumble at Kentuckys 10 was recovered by the Wildcats Courtney Love with 1:45 left. Stephen Johnson then led Kentucky (7-5) downfield and into position for MacGinnis game-winning kick that ended Kentuckys five-game losing streak in the series.I had great confidence in him, Kentucky coach Mark Stoops said of MacGinnis. I was numb. I just wanted to finish it.Jacksons desperation heave as time expired from deep in Louisville territory was intercepted by Mike Edwards, his second pick of the game, and set off a wild celebration among the Wildcats and their fans.MacGinnis might have been the happiest Wildcat, having earlier saved Kentuckys season with a 51-yard kick to beat Mississippi State . This one provided the programs first seven-win season since 2009.As soon as we got that fumble I knew my team was going to give me a chance, said MacGinnis, who also kicked a 35-yarder. I cant give enough love to my snapper and holder.Jackson likely could have wrapped up the Heisman with his record-setting day, but a second consecutive loss could impact the race. Jacksons day included three interceptions -- one of which was converted into a touchdown -- and his late fumble led to the game-winning kick.Louisville running back Brandon Radcliff, however, said this loss was not Jacksons fault.He got us all these wins, Radcliff said. Hes a great player. The competitive spirit hes got, hes always going to put it on himself. Nobody in this locker room believes this (loss) is on Lamar.Jackson tallied his school-record eighth 100-yard rushing game and broke the Louisville season mark for rushing yards. His four touchdowns also broke the Atlantic Coast Conference single-season record (he has 51), but the Cardinals (9-3) were left wondering what might have been -- again.Sometimes in this game, you find ways to win and sometimes you find ways to lose games, Louisville coach Bobby Petrino said. I certainly feel like we found a way to lose that game. Give Kentucky credit.POLL IMPLICATIONSLouisville will likely drop again in the poll with its second straight loss, the question may only be how far.THE TAKEAWAYKentucky: Stephen Johnsons season-long success with deep post passes continued in the first half with TDs that kept the Cardinals on their heels. His touchdown passes covered 75 and 63 yards to Garrett Johnson and 35 to Dorian Baker. More importantly, he didnt flinch in the clutch, hitting key passes and running on Kentuckys final drive. The Wildcats outgained Louisville 581-561.I had a missed throw that couldve sealed the game, said Johnson, who was named the games Most Valuable Player. Im really happy with the offense.Louisville: Jackson accounted for four touchdowns and 452 yards (171 rushing, 281 passing) and broke Howard Stevens 1,429 yards rushing mark in 1971. He also broke the ACC single-season record for TDs accounted for previously held by Clemsons Deshaun Watson. Turnovers, however, were too costly to overcome as Jackson threw three interceptions.UP NEXT:Kentucky: Awaiting bowl destination.Louisville: Awaiting bowl destination.---More AP college football: www.collegefootball.ap.orgJoel Eriksson Ek Wild Jersey . The 28-year-old from Calgary matched his career best after missing just one shot in his two rounds of shooting in the mens 10-kilometre sprint competition. Smith finished in 23 minutes 15. Zach Parise Wild Jersey . Following a lopsided 5-2 loss against the New Jersey Devils on Wednesday night, Paul MacLean told reporters that "theres a lack of focus, theres a lack of leadership and theres a lack of preparation" with his struggling team. That came on the heels of Bryan Murray taking the unusual step of going into the locker room at the Prudential Center and addressing the players himself. http://www.authenticwildpro.com/Mikko-koivu-wild-jersey/ . James, who turned 29 on Monday, injured his groin Friday during the Heats overtime loss at Sacramento. He sat out the following game, a 108-107 win Saturday in Portland, before coming back to help send the Nuggets to their seventh consecutive loss. Jason Zucker Jersey . -- Bryant McKinnie came out of his stance and lowered his shoulder into a practice squad player, causing a crisp thud to reverberate in the Miami Dolphins practice bubble. Minnesota Wild Jerseys . JOHNS, N.Pittsburgh Steelers wide receiver Martavis Bryant has been banned for the entire 2016 season for a violation of the NFLs drug policy.Bryant, who served a four-game ban last season for a violation of the substance abuse policy, will not be eligible for reinstatement for a minimum of 12 months - the suspension starts immediately.The 24-year-old proved productive after his ban last season, piling up 50 receptions for 765 yards and six touchdowns in the 11 games he played.Bryant dropped to the fourth round of the 2014 NFL Draft because of concerns over his off-field behaviour during his time in college at Clemson.One of Bryants agents, Brian Fettner, said on Sunday his client was suffering from depression and was seeking to enter rehab.Were all stunneed, me included, Fettner told USA Today.dddddddddddd We clearly miscalculated the issue. His isnt a party issue. Its a coping issue and a depression issue, and hes got to take care of it.This is the biggest cry for help Ive ever seen, and that hurts. It hurts us to see.Hes 24 years old, and hes got to get right, whatever it is. If you talk to anybodys family that has depression, they will be talking about these same things - the [despondence], the withdrawal, the head-in-the-sand despair - just trying to cope.Also See:NFL free agency updatesNo Fitzpatrick in DenverWhat next for Kaepernick?Browns release Manziel ' ' '